Enabling [(18)F]-bicyclo[6.1.0]nonyne for oligonucleotide conjugation for positron emission tomography applications: [(18)F]-anti-microRNA-21 as an example.

نویسندگان

  • Xiang-Guo Li
  • Anne Roivainen
  • Jörgen Bergman
  • Arttu Heinonen
  • Frank Bengel
  • Thomas Thum
  • Juhani Knuuti
چکیده

A bicyclononyne-based prosthetic group has been developed for (18)F-labeling of anti-microRNA-21, an oligonucleotide, in a near-stoichiometric manner.

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عنوان ژورنال:
  • Chemical communications

دوره 51 48  شماره 

صفحات  -

تاریخ انتشار 2015